Research Paper Submissions

Researchers report superconductivity at 294 K (21°C / 70°F) in nitrogen-doped lutetium hydride at 10 kbar pressure - the closest yet to ambient conditions. If replicated, this could revolutionize energy transmission and quantum computing.

This paper introduces a generative AI that designs efficient synthesis routes for organic molecules, potentially accelerating drug development and materials science by automating one of chemistry's most complex challenges.

Using large-scale neural recordings, researchers mapped how prior expectations are encoded across the entire mouse brain during perceptual decisions. The findings reveal a distributed network that updates beliefs based on experience - key to understanding how brains make predictions.

A pilot clinical trial shows that epidural spinal cord stimulation (SCS) in spinal muscular atrophy, a neurodegenerative disease, can revert motorneuron dysfunction and improve motor function. This technology is becoming unavoidable for treatment of motor disorders and could be used with BCI

This paper is pretty recent (december 17th) shows a new way to boost aging immune systems. The researchers deliver mRNA to the liver so it briefly produces a small set of proteins that the body normally uses to build and maintain immune cells, specifically T cells. In old mice, this restored key immune function, leading to stronger vaccine responses and better anti-tumor immunity. Big picture, it demonstrates a “programmable medicine” approach where the liver can act like a temporary drug factory (kinda like the iDegs paper), releasing precisely tuned immune signals. This has potential to reduce risk of immunotherapies like vaccines inducing some sort of chronic or unlocalized inflammation response (with caveats).